All About Psoriatic Arthritis Treatment

You need to know about current treatments for the disease

Psoriatic arthritis is a common chronic joint disease associated with a skin condition called psoriasis. Patient treatment options have changed significantly over the past decade. In order to prevent joint deformation, every victim should know how to treat psoriatic arthritis. Clinical studies provide insight into the true value of NSAIDs for joint arthritis. Biological agents and tumor necrosis factor inhibitors are widely used. The treatment strategy is individual. Gradually, new agents are being introduced into the pharmaceutical market to help ensure better future prospects for the patient. 



Non-steroidal anti-inflammatory drugs (NSAIDs)

There is no cure for psoriatic arthritis. With the help of drugs, you can prevent acute attacks of arthritis and slow the progression of the disease. Non-steroidal anti-inflammatory drugs are effective for many patients. NSAIDs inhibit pain, relieve swelling and morning stiffness, and improve the range of motion of the joints in psoriatic arthritis. An incomplete list includes (the active ingredient is indicated in brackets): 

  • Clinoril (sulindac);
  • Clitoris (piroxicam);
  • Indocin (indomethacin);
  • Mobic (meloxicam);
  • Motrin, Advil (ibuprofen);
  • Dock, Anaprox, Naprelan, Naprosin (naproxen sodium);
  • Relafen (nabumetone);
  • Voltaren, Artrodoc (diclofenac).

Which NSAIDs can be used will be decided by the doctor, each case is individual and requires a special approach. Acetaminophen and Tylenol can be added to the list of drugs for pain and inflammation relief. These medicines are available without a prescription. Stronger NSAIDs are available with a prescription. Some medicines, when taken in high doses or over a long period of time, cause problems in the gastrointestinal tract, including ulcers and bleeding. 

COX-2 and PDE4 inhibitors against joint inflammation

Numerous studies show that COX-2 inhibitors are less problematic for the stomach than NSAIDs. For example, Celecoxib (Celebrex) is also an NSAID, but a different type that has a stronger effect and a lower risk of side effects in psoriatic arthritis. It is only available with a prescription. COX-2 inhibitors reduce pain and inflammation with less harm to the stomach, but they do cause heart problems. They have many risks, so before using them, you should discuss the drug with your doctor, take into account all the pros and cons 

A new treatment option for psoriatic arthritis is PDE4 inhibitors. Currently, Ampremilast is one of the best drugs for this type of arthritis. The new oral agent regulates complex inflammation processes within the immune cell, which leads to the reduction of edema and pain relief. The drug inhibits an enzyme known as phosphodiesterase 4, or PDE4. PDE4 controls most of the inflammatory actions in cells that affect the level of inflammation associated with psoriatic arthritis. Ampremilast should be taken continuously to maintain the improvement achieved. 

A new treatment option for psoriatic arthritis is PDE4 inhibitors. Currently, Ampremilast is one of the best drugs for this type of arthritis. The new oral agent regulates complex inflammation processes within the immune cell, which leads to the reduction of edema and pain relief. The drug inhibits an enzyme known as phosphodiesterase 4, or PDE4. PDE4 controls most of the inflammatory actions in cells that affect the level of inflammation associated with psoriatic arthritis. Ampremilast should be taken continuously to maintain the improvement achieved.



Disease therapy with basic anti-inflammatory drugs

DMARDs are prescribed to slow the potential joint damage caused by psoriatic arthritis. Unlike NSAIDs, they take longer to take effect. Some antirheumatic drugs that reduce pain and inflammation in psoriatic arthritis but have many side effects when treated:

  • Methotrexate;
  • Sulfasalazine;
  • Cyclosporine;
  • Leflunomide.

Methotrexate is an immunosuppressive drug approved for the treatment of psoriatic arthritis. It is effective in relieving symptoms and preventing joint destruction. Small doses of methotrexate are generally well tolerated. However, the drug has a number of side effects, and exaggerating the dose of the drug can damage the liver. A patient taking methotrexate should carefully follow the doctor’s instructions.

Sulfasalazine, a sulfa drug developed to treat inflammatory bowel disease, is sometimes used for psoriatic arthritis. The use of the drug is not recommended for patients suffering from porphyria, impaired metabolism, diseases of the urinary tract. The doctor may require regular blood tests while the patient is on Sulfasalazine, which is required to treat psoriatic arthritis. This is necessary to monitor the number of leukocytes and liver enzymes. Possible side effects: nausea, rash, headache, abdominal pain, vomiting, fever, and dizziness.

If these medications do not bring the desired result, the doctor will prescribe biologics. This is a new type of BPVP. They block a protein that causes inflammation in the joints. These biological products include:

  • Adalimumab;
  • Certolizumab;
  • Etanercept;
  • Golimumab;
  • Infliximab;
  • Ustekinumab.

These medicines are expensive and have side effects (dizziness, nausea, vomiting, abdominal pain). They reduce the response of the immune system to the body’s defense against an infectious or viral disease.

What is Provailen and how does it work?

Provailen is a potent homeopathic immune system modulator used for rheumatoid and psoriatic arthritis. It is a natural remedy formulated with herbs, medicinal mushrooms, vitamins and minerals. Benefits:

  • quickly relieves pain;
  • reduces inflammation and swelling;
  • stops the progression of the disease;
  • improves adrenal function.

It also promotes quick healing. Due to this, the cartilage tissue damaged by psoriatic arthritis is gradually restored. In fact, Provailen outperforms many drugs that actually poison the body and cause many diseases. This remedy has been successfully used against various types of arthritis for many decades, only a few know about it. Provailen brings patients back to life.

Diet food for illness

The diet for psoriatic arthritis plays an important role in reducing inflammation. By adjusting the diet, all manifestations of arthritis can be controlled. Talk to your doctor before making any major changes in your eating habits. There are 3 approaches to diet:

  1. Weight loss. The researchers found that a high body mass index (BMI) was associated with an increased risk of psoriasis and psoriatic arthritis, as well as an increased severity of the disease. Eliminate foods that contribute to weight gain.
  2. Eating anti-inflammatory foods. Most people respond positively to dietary changes to combat chronic inflammation. To reduce inflammation, include flaxseeds, olive oil, pumpkin seeds, walnuts, low-fat fish, fresh fruits and vegetables (blueberries, mango, figs, squash, carrots, cabbage, broccoli), omega-3 fatty acids in the diet.
  3. A gluten-free diet for psoriatic arthritis will significantly improve the patient’s condition. She completely excludes from the diet foods containing a complex protein compound – gluten. You can eat rice, corn, poultry, meat, fish, legumes and most dairy products, vegetables and fruits.

According to the National Psoriasis Foundation (NPF), there is little scientific evidence that diet affects the symptoms of the disease. However, many people claim that avoiding certain foods can help manage the intensity of arthritis. Avoid fatty red meats, processed foods, refined sugar, nightshade vegetables (tomatoes, peppers, potatoes), and high-fat dairy products.


Nutrition Tips

Psoriasis arthritis is an inflammatory disease that requires proper treatment and nutrition. Here are some guidelines to follow for this disease:

  1. Eat fish at least twice a week. For example, tuna, mackerel, herring, trout.
  2. Choose lean meats and skinless poultry. Cook them without adding saturated fat or trans fat.
  3. Use low fat dairy products.
  4. Limit food containing partially hydrogenated vegetable oils. They contain trans fats.
  5. Limit your alcohol intake.
  6. Limit processed foods and fast food.

In addition, vitamins must be included in the diet. Studies have not shown a direct link between vitamins and dietary supplements for psoriatic joint disease. However, doctors note that they help clear the skin and relieve pain. Supplements are sold in capsules, tablets, powders, and liquids. Glucosamine can aid in the formation and repair of cartilage and possibly reduce inflammation. Chondroitin increases the elasticity of cartilage tissue and inhibits its destruction.

Doctors strongly recommend adding vitamin D to the diet. The safest source of vitamin D is fish oil, salmon, mackerel, orange juice, eggs, cheese, fortified cereals. 

Organization of the therapeutic process at home

You can protect joints from destruction and inflammation with the help of folk remedies. Herbs used for baths have proven to be successful. Chamomile, nettle, linden, calamus root, willow bark and string have amazing properties. Take a bath with the addition of one of the listed herbs should be 15-30 minutes, preferably every day. Treatment of psoriatic arthritis with folk remedies is less expensive than drugs. Here are some effective recipes:

  1. Linseed compress. With the cotton cloth ready, heat the flax seeds in a skillet. Then pour the raw material into the fabric and wrap the sore joints. The procedures are performed daily before bedtime.
  2. Lingonberry tea. Pour two teaspoons of crushed lingonberry leaves with a glass of boiling water. After a 15-minute infusion, tea is drunk in small sips. Add honey if desired.
  3. Burdock root infusion. 300 grams of chopped grass is poured with vodka so that its level is 3 cm higher than the leaves. The medicine is insisted in a dark, warm place for 3 weeks. The resulting product must be rubbed daily with the affected joints.

In addition to treatment with folk remedies, be sure to get plenty of rest, eat well, and avoid heavy stress on the joints. 



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