Uric acid with gout does not have time to be excreted and accumulates in the body. In certain volumes, this substance even benefits, but its excess in the blood is precisely the main provocative factor in the development of gout.
Urates (crystals) accumulated in the joint tissue gradually destroy it. Therefore, it is important for healthy people and those who suffer from gout to know about normal uric acid levels in the body.
Each person is genetically embedded in his own normal value of the substance in question in the blood. With the proper functioning of the body, this level is constantly maintained, and the excess is excreted by the kidneys.
What indicators are considered the norm:
- 70-300 micromol / l among infants 0-12 months;
- 120-300 micromol / l under the age of 14 years;
- 200-420 μmol / l among men under the age of 40;
- 240-400 micromol / l among men 40-60 years old;
- 250-500 μmol / L among men over 60;
- 210-550 μmol / l among men over 80 years old;
- 150-350 μmol / l in women under the age of 40;
- 210-450 μmol / l among women 40-80 years old;
- 150-480 micromol / l in women older than 80 years.
With gout, the state of a person depends on the level of uric acid. If it is stably increased, then the process of destruction of the joint tissue occurs faster, and the symptoms are manifested more often and painfully.
An increase in the performance of this substance in the body may be temporary. For example, this happens after eating a large portion of a meat dish. Also, the indicators of the substance in question increase in athletes taking protein supplements, or in people, on the contrary, adhering to a strict diet. However, after the exclusion of provoking factors, the acid content quickly returns to normal. But a regular excess of this substance is called hyperuricemia.
Causes of accumulation and consequences
During the breakdown of proteins, uric acid is formed. Entering into connection with potassium or sodium, this substance provokes the deposition in the tissues of urates. According to statistics, with gout, the joints of the extremities are most often inflamed. Uric acid precipitates in these zones to a greater extent. This is due to the fact that in the fingers of the hands and feet the temperature and blood circulation are reduced.
The danger is that excess acid in the joints is practically unable to dissolve in water. In this regard, in addition to the disease in question, a person develops a number of pathologies: arthritis, kidney stones. If uric acid cannot be controlled with gout, then the risk of developing cardiovascular diseases, diabetes mellitus, and renal failure increases.
The level of uric acid with gout in men and women is not the same, as are normal indicators in the absence of the disease. To determine it, the patient donates blood for biochemical analysis. The results are evaluated depending on deviations from the norm, taking into account age and gender.
If the uric acid index is increased in the analyzes, this is not yet a sign of gout. But in the presence of alarming symptoms in the form of discomfort in the kidneys and joints, the patient is recommended to undergo a more thorough examination. Diagnosis of gout includes rheumatoid tests, ultrasound, MRI .
For preventive purposes, doctors recommend at least once every 6-12 months to donate blood for a biochemical study. Timely diagnosis of the disease allows you to prescribe the correct treatment, extend the period of remission and reduce the frequency of exacerbations.
Ways to lower the level
In women and men, uric acid with gout can be returned to normal only with complex treatment. Indicators 200-550, depending on age, help to achieve a special diet and medication. Women need to get close to 200-480. Ways to lower the level:
- Drug therapy consists in the lifelong administration of drugs that promote the excretion of uric acid (Sulfazole, Anturan, Uriconorm). The courses prescribe drugs that reduce production and help to dissolve this component (Tiopurinol, Blemaren, Allopurinol , Soluran, Orotic acid). Read more about medicines for gout →
- Dietary nutrition for gout helps stabilize uric acid levels. Patients are advised to abandon fried, fatty foods, broths, marinades, canned goods, smoked meats, alcohol. It is important to minimize salt intake and control the drinking regime (drink at least 2 liters of clean water per day).
Observing all the doctor’s recommendations regarding drug therapy and diet, people with gout often manage to keep uric acid values within normal limits. At the same time, the process of destruction of joint tissue slows down, and health improves.
Posted by Tatyana Grosova, doctor,
specially for Ortopediya
Read this also:
- How can uric acid be removed from the body with gout?
- How to reduce uric acid levels from blood
- How to lower uric acid levels
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