Mesenchymal stem cells have recently gained popularity for the treatment of rheumatoid arthritis (RA). And are currently the subject of several clinical trials. The search for more effective treatment methods was caused by the limitations of modern RA treatment methods. Preliminary results show that mesenchymal stem cells are a new promising means of improving pain. As well as inflammation and the overall quality of life of the patient. In this article, we consider the treatment of rheumatoid arthritis with stem cells. Morning stiffness with rheumatoid arthritis .Stem Cell Treatment for Rheumatoid Arthritis

Stem Cell Treatment for Rheumatoid Arthritis

Rheumatoid arthritis is an autoimmune disease, a condition in which the body’s own immune system mistakenly attacks healthy cells. The immune response observed in patients with rheumatoid arthritis leads to inflammation and swelling of the joints. Which ultimately causes cartilage destruction and bone fusion. Most often, the joints of the hands, feet and cervical spine are affected. Understanding the complex immune pathways that lead to joint inflammation has served as the basis for targeted therapy that reduces the inflammatory response. The greatest limitations of modern therapy include patient intolerance, toxicity, risk of infections. And, in some cases, only a partial response with ongoing joint pain and damage. Because of these limitations, new therapeutic strategies are needed.

Stem Cell Treatment for Rheumatoid Arthritis

Mesenchymal stem cells are immature cells that can divide and turn into a number of different specialized cells in the body. Including fat, bone and cartilage cells. It is important to note that, making them somewhat ideal for use in the treatment of immune-related diseases, such as rheumatoid arthritis. Mesenchymal stem cells have recently demonstrated anti-inflammatory and immunosuppressive effects.

A recent study tested the safety of mesenchymal stem cells in the treatment of rheumatoid arthritis. In particular, stem cells derived from the umbilical cord were used. Because they are more accessible and have a greater ability to reproduce. The results of this preliminary study were promising. Showing a general reduction in joint pain, swelling, and stiffness in patients. Effects were observed twelve hours after treatment and lasted up to three months. The supposed cause of a positive response in patients was a decrease in pro-inflammatory factors in the blood. In addition, it has been found that a subset of immune cells called T cells, which play an important role in suppressing autoimmune reactions, increases in the peripheral blood of treated patients. Diagnostic methods of RA .

Additional clinical trials are underway to evaluate the safety and effectiveness of mesenchymal stem cells in the treatment of rheumatoid arthritis. In these trials, patients will receive an intravenous infusion of stem cells at various intervals. The primary measure of these studies is safe for use in patients. Other measured outcome measures include disease progression markers, patient quality of life indicators, and pain scores. Two studies evaluate the use of mesenchymal stem cells alone. An alternative study will also evaluate the effect of mesenchymal stem cells, administered in combination with traditional therapy for the treatment of rheumatoid arthritis.



Previous research and emerging clinical findings suggest that mesenchymal stem cells may be a new hope for patients with RA. In addition to the demonstrated anti-inflammatory properties of these cells, they can also be a source of growth factors. Therefore, it has been suggested that they may even play a role in protecting the affected tissue from further damage. Or damage in addition to accelerating tissue repair. More research is needed to determine the exact mechanisms of action. And corresponding benefits for patients with rheumatoid arthritis. How to cope with RA ?

Stem Cell Treatment for Rheumatoid Arthritis


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