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Rheumatoid arthritis is a fairly common disease associated with joint pathology. Due to the development of the disease, tissue inflammation, degeneration and various complications are observed. Rheumatoid arthritis is sometimes associated with the presence of bacterial pathogens. For this reason, in some cases of the development of pathology, it is not enough to use drugs, the pharmacological action of which is aimed at analgesia and eliminating puffiness and inflammation. Antibiotics for rheumatoid arthritis are taken to effectively affect the causative agent of the disease, but in most cases this form of the disease does not need to be treated by this method – bacteria that multiply in the tissues of the joint contribute to the cessation of the disease. Thus, the indications for the use of these drugs should be clearly established.
Treatment of rheumatoid arthritis with antibiotics is strictly according to certain indications. The indications for the use of antibiotics for rheumatoid arthritis are as follows:

  • Purulent form of the disease. It is possible to recognize the presence of pus in a joint by some signs, such as:
    • hyperemia of acute type;
    • severe swelling;
    • bright redness of the skin in the area of ​​the inflamed joint;
    • more pronounced pain.
  • Disease prevention in case of frequent and long-term infectious diseases
  • Prevention of the disease in case of exacerbation of diseases associated with tissue inflammation:
    • pyelonephritis;
    • bronchitis;
    • sinusitis;
    • tonsillitis;
    • other.
  • Immunodeficiency that developed as a side effect after taking pharmacological drugs. With immunodeficiency, intestinal dysfunction may develop, which is also an indication for taking antibacterial agents.

Release form

Patients looking for a “super antibiotic” for rheumatoid arthritis should take into account the doctor’s indications and the form of the disease. Treatment of rheumatoid arthritis with new generation antibiotics is possible strictly according to indications, namely, with suppuration in the joint, for prophylaxis in the presence of other inflammatory or infectious diseases and with immunodeficiency. If necessary, a specialist may prescribe an antibiotic for an exacerbation of rheumatoid arthritis.

Mediums of effective medicinal antibacterial agents are isolated “Minocycline” (“Minocin”, “Minolexin”) – an antibacterial agent of the tetracycline series of semisynthetic origin, which can effectively act on pathogens in the initial stage. After use, puffiness, pain decreases and the ability to move less constrained appears.

The release form of the drug is tablets, capsules and suspension.

Arthritis and arthrosis are joint diseases that are now quite common, and not only in old age. The disease can begin to progress at any time. There are many reasons that can provoke the development of a pathological process, ranging from infectious processes to a banal sedentary lifestyle. If the disease becomes chronic, irreversible processes begin in the joints, which can lead to complete restriction in movement and disability. Are arthritis and arthrosis treated with antibiotics? What is the peculiarity of their use and what is the treatment regimen, we will consider further.

What kind of disease arthritis and arthrosis

Arthritis is a disease characterized by an inflammatory process in the joints, accompanied by constant pain. With arthritis, there is a thinning of the cartilaginous cartilage, changes in the ligaments and the joint capsule. The disease can develop at a young age. In old age, it develops against the background of arthrosis.

Arthrosis is a disease in which dystrophic changes in cartilage tissue occur, while there is no inflammatory process. As a rule, this pathology is characteristic of an aging body. In some cases, it develops after injuries, serious illnesses. Common in athletes. Arthrosis is of two types:

  • Primary. The cause may be a violation of blood supply and tissue nutrition.
  • Secondary develops after injuries or joint damage.

Arthrosis is not accompanied by an inflammatory process, therefore, does not require the use of antibiotics.

These two diseases are inextricably linked. So, after suffering arthritis, irreversible changes in the joints may occur, as a result, the disease will develop into arthrosis. When an inflammatory process joins the degenerative processes in arthrosis, arthritis also develops.

Types of arthritis

There are several types of arthritis:

  • Infectious. The inflammatory process in the joints developed against the background of infection.
  • Rheumatoid arthritis. It develops against a background of allergic and infectious diseases. Can develop into chronic.
  • Reactive arthritis is triggered by sexually transmitted infections, viral or colds.
  • Juvenile arthritis is not fully understood. It can develop in children under 16 years of age against the background of damage to the immune system of healthy tissues.

Next, consider what antibiotics to take for arthritis.

How to choose an antibiotic

If pain occurs in the joints, then this is a sign of an inflammatory process. Before prescribing an antibacterial agent, the doctor must clarify the following facts:

  • The focus of inflammation.
  • The reason for the development of pathology.
  • The causative agent of the infection.
  • The sensitivity of microorganisms to the active substance of the antibiotic.

Depending on the pathways through which the infection has entered the body, such antibiotics are prescribed for arthritis:

  • Tetracyclines. If the cause is urogenital infections.
  • Penicillins and cephalosporins. For upper respiratory tract infections.
  • Fluoroxyquinolone group. With intestinal infections.

Antibiotics for treating infectious arthritis

Treatment of infectious arthritis in the acute phase requires inpatient treatment, since the disease must be kept under control. An untreated infection will lead to even greater complications. Timely prescribed antibiotics for arthritis can eliminate the cause and avoid possible complications. They form the basis of treatment. After a few days of admission, the patient feels better.

In the course of treatment, the first days of taking the medicine are very important. As a rule, drugs of the penicillin series are used:

Depending on the type of infection, antibiotics are selected for infectious arthritis.

Features of the treatment of infectious arthritis

The doctor determines how effective the selected antibiotic is, and whether there is a need to add another one to enhance the therapeutic effect. Treatment tactics are as follows:

  • The affected joint must be provided with complete rest and immobilization.
  • Next, the joint is washed and excess fluid is removed.
  • Drainage is performed if infectious arthritis does not respond to antibiotic therapy.
  • Antibiotics for arthritis are given intravenously and directly to the affected joint.
  • In addition to antibacterial drugs, pain relievers and restorative drugs are prescribed.
  • If antibiotic therapy is ineffective, surgery is possible.

Antibiotics for rheumatoid arthritis

Rheumatoid arthritis is accompanied by pathological processes. The appointment of antibacterial treatment contributes to the speedy recovery of the patient. It is important to start effective therapy early in the disease. In what cases are antibiotics prescribed for rheumatoid arthritis:

  • If there is an infectious and inflammatory process in the joints.
  • For prophylaxis against lingering infectious diseases.
  • To avoid complications during exacerbation of chronic diseases such as tonsillitis, sinusitis, pyelonephritis, bronchitis. The course of such diseases contributes to the development of rheumatoid arthritis.
  • In case of intestinal dysfunction, as a result of prolonged use of drugs used to eliminate articular pathology.
  • For prophylactic and therapeutic purposes with immunodeficiency, which has arisen as a result of the treatment of rheumatoid arthritis.

Complex treatment is used to treat rheumatoid arthritis, which includes:

  • Antibiotics.
  • Anti-inflammatory drugs.
  • Pain relievers.
  • Physiotherapy.
  • Manual therapy.

What antibiotics are used for rheumatoid arthritis and according to what scheme – read on.

Treatment regimen for rheumatoid arthritis

For treatment, antibiotics of the following groups are used:

The application scheme is as follows:

When carrying out antibiotic therapy, drugs are prescribed to improve the intestinal microflora. Antibiotic treatment for rheumatoid arthritis allows the patient to get back on their feet quickly.

During treatment, it is very important to follow a diet, quit smoking and drinking alcohol.

Antibiotics for reactive arthritis

With reactive arthritis, an antibiotic is inevitable. Chlamydia, salmonella and shigella become the cause of the disease. Here are some guidelines for treating reactive arthritis:

1. The following antibiotics are used for treatment:

2. Treatment should be carried out for at least 7 days.

3. After the course of treatment, after 3 weeks, it is necessary to re-take the tests.

4. If chlamydia is found, then it is necessary to check for other genital infections.

5. During treatment and after 7 days, refrain from sexual intercourse.

6. The partner must undergo a similar course of therapy.

Fight arthritis of the foot

Arthritis of the foot is a disease that is accompanied by pain when moving. It will get stronger over time. A prolonged inflammatory process contributes to tissue degradation. The treatment regimen is as follows:

If the disease is constantly masked with painkillers, the joints of the foot will collapse and there will be great difficulties in movement.

Adverse reactions of antibiotic therapy

As you know, antibiotics kill not only pathogenic microflora, but also useful. An improperly prescribed antibiotic can aggravate the situation, and the disease will become chronic. Therefore, it is necessary that only a doctor prescribes medications. Antibiotic treatment for arthritis can lead to side effects, such as:

  • Decreased body immunity.
  • Disorder of the digestive system.
  • Change in healthy microflora.
  • Changes in blood counts.
  • Anemia.
  • Headaches, dizziness.
  • Sleep disturbances.
  • General weakness, loss of strength.
  • Skin rashes.
  • Swelling, itching, irritation.
  • Decreased body resistance.

It is also possible intolerance to the constituent drugs or the active substance. Therefore, it is best to use antibiotics for arthritis in hospital treatment.

With home therapy, strictly follow the treatment regimen and the dosage of the drug.

Antibiotic recommendations

To combat the infection and cope with a disease such as arthritis, antibiotic treatment should be under the supervision of a doctor. You also need to adhere to some rules when taking antibiotics:

  • You need to take an antibiotic only as directed by a doctor.
  • To find the right medicine, you need to pass tests for bacterial culture.
  • When taking the prescribed drug, strictly observe the time and frequency of administration.
  • Take the medicine for as many days as the doctor prescribed, even if you feel an improvement in your condition.
  • It is impossible to interrupt the course of treatment.
  • Do not reduce or increase the dosage on your own without consulting your doctor.
  • It is correct to take antibiotics: drink only clean water, clarify the combination of medicine with food intake.
  • Together with antibiotics, take medications that support the normal intestinal microflora.
  • Stick to a diet. Exclude smoked, salted, fatty and fried foods. Eat more fermented milk products.
  • You must not smoke or drink alcohol. Especially when treating arthritis.

I would also like to note that in order to prevent arthritis, one should deal with excess weight so as not to burden the joints, play sports, follow a diet and get rid of bad habits. This pathology is quite insidious, you can get rid of it only by timely measures. Compliance with all the doctor’s recommendations, changing the lifestyle, adjusting the diet are inevitable measures on the way to recovery.


  1. What is rheumatoid arthritis?
  2. Anti-inflammatory drugs of the first group
  3. Biologicals of the second group
  4. Tumor necrosis factor (TNF) drugs
  5. Glucocorticoid drugs
  6. The use of narcotic and non-narcotic analgesics

The method of treatment of intensive drug therapy directly depends on the individual character of the organism, which is distinguished by its own individual reaction to external influences: these are the peculiarities of the metabolism, unwanted reactions to medications, genetic heredity at the molecular level.

What is rheumatoid arthritis?

In rheumatoid arthritis, an infection develops, affecting the entire body as a whole, increasing the number of leukocytes in the blood. The disease has a detrimental effect on the erythrocyte sedimentation rate. For this reason, there is a violation of the immune system, damage to tissue and joints. The task of the attending physician is to make an accurate diagnosis, relieve pain, slow down the progression of the disease and restore a weakened body, if possible.

Most often, the doctor prescribes an increased dose of the medication. For rheumatoid arthritis or rheumatism, good medications are needed to relieve the inflammation without causing side effects. Treatment of the disease should be comprehensive. In this case, antibiotics are most often used. If a risk factor arises, the direction of therapy is changed, and another medical treatment is prescribed. In this case, the use of strong antibiotics is simply unacceptable.

When treating rheumatoid arthritis or rheumatism, it is necessary to find a middle ground that will help relieve the inflammatory process and suppress a serious ailment. An individual approach to the characteristics of the body, the correct decision of the attending physician will help here.

In order to fully control the state of the body, the patient is prescribed inpatient treatment. A constant examination by a doctor, tests and a complete examination will help to make the correct diagnosis. This is also done in order to normalize the dosage of drugs to a minimum, since any pills have their own side effects.

Sometimes drugs are prescribed, which are classified into subgroups: non-steroidal anti-inflammatory drugs (NSAIDs), biological response modifiers, antibiotics that are active during rheumatoid arthritis disease, analgesics.

Anti-inflammatory drugs of the first group

These antibiotics are prescribed to relieve pain and reduce inflammation. But anti-inflammatory drugs are not effective in the advanced form of the disease. The drugs are used with precise regularity, strictly in a certain dose. A gradual increase in the dosage of drugs is prescribed by the attending physician in case the symptoms persist or another treatment is prescribed.

Some anti-inflammatory drugs have severe side effects. They can cause gastrointestinal bleeding, fluid retention in the body. Taking them may increase the risk of developing cardiovascular disease. And therefore, each drug must be weighed against the danger so as not to acquire new ailments.

With rheumatoid arthritis or rheumatism, medications are prescribed that affect the course of the disease itself. Basic drugs reduce function by affecting the joints, while maintaining the structural integrity of the entire body. Patients diagnosed with rheumatoid arthritis and rheumatism return home after treatment and lead the same way of life. These drugs work much more slowly, but they are more effective and do not cause severe side effects, along with other drugs. Glucocorticoids are taken in small doses to relieve inflammation and pain.

These include:

  • Azathioprine,
  • Cyclosporine,
  • Leflunomide,
  • Hydroxychloroquine, etc.

Methotrexate should be used for four to six weeks to somehow alleviate the symptoms of rheumatoid arthritis. Sulfasalazine is taken for one to two months. Hydroxychloroquine is used for up to three months. When using this or that medicine, it is necessary to take into account the individual characteristics of the organism. Some drugs have little effect on the disease. In this case, a longer treatment will be required than anticipated.

Many patients with rheumatoid arthritis, using minocycline, can feel a strong relief of the whole body. This alternative treatment helps more than the use of hydroxychloroquine or sulfasalazine.

Biologicals of the second group

Biologics are used to prevent inflammation in the joints. Treatment directly depends on the condition and development of the disease. Biologics act directly on molecules. There are several types of these drugs that target molecules. It may be tumor necrosis factor interleukin-1, a molecule on the surface of T- and B-lymphocytes. Regular connection in some diseases enhances the development of autoimmune reactions in the body.

Tumor necrosis factor (TNF) drugs

This group includes the following drugs:

  • Etanercept,
  • Blockers,
  • Infliximab,
  • Adalimumab.

Some drugs are less effective for rheumatoid arthritis. Therefore, another medicine is prescribed, given the history of the disease. The use of anakinra concomitantly with TNF-blockers is prohibited. Since the immune system is too weak in rheumatoid arthritis, there is a risk of contracting new infectious diseases.

Abatacept (Orencia®) is prescribed for severe symptoms of rheumatoid arthritis. The disease can manifest itself moderately, without any pathology or deterioration. This medication interferes with the activation of T cells in the progressive development of rheumatoid arthritis disease.

Rituximab (Rituxan®) counteracts the development of B cells. This medication is given when other drugs have failed or the form of the disease has suddenly worsened.

Biologics are given by injection, by a nurse, and parenterally. Humira, enbrel and kinneret are injected subcutaneously by the patient himself or his friends. Remicade, orentia and rituxan – intravenously, with an interval of one to three hours. Some medicines are forbidden to be used by patients with especially dangerous infections.

The effect of basic drugs is revealed after some time, sometimes months can pass. Rituxan, orentia – partial recovery, up to 6 weeks. The actions of biological drugs, which are prescribed for rheumatoid arthritis, rheumatism, appear very quickly. Enbrel, humira, remicade give an effect after 2 weeks of admission. The result of recovery can only be said by the attending specialist after a complete medical examination.

Sometimes, due to the cost of the medication, the patient is prescribed basic drugs, but only if the development of the disease of rheumatoid arthritis or rheumatism is not in a complex form. However, this does not guarantee a complete recovery.
It is important to have a medical examination for TB beforehand if your doctor has prescribed TNF blockers. Patients who have confirmed tuberculosis first cure this ailment. This is because TNF blockers increase the risk of developing microbacteria. Medicines are contraindicated when a node lymphoma is detected, as they put them more at risk of developing the disease.

Glucocorticoid drugs

Glucocorticoid drugs (glucocorticoids) are prescribed for rheumatoid arthritis or signs of advanced rheumatism. The medicine quickly removes the anti-inflammatory process. Medicines prednisone or prednisolone reduce swelling, pain and inflammation in the joint area. Rheumatism is weakened, the working capacity of the whole organism increases, up to complete recovery.

It is not recommended to use antibiotics alone, they are more effective with other drugs. Self-medication and suspicious pills that can cause side effects are also not encouraged.

The use of narcotic and non-narcotic analgesics

For rheumatoid arthritis or signs of rheumatism, non-narcotic analgesics are often prescribed. They quickly relieve pain and inflammation without causing any complications. But you should know that the doctor prescribes them not for all patients, but individually, depending on the development of their disease.

Subgroups of non-narcotic analgesics, tablets:

  • Paracetamol,
  • Acetylsalicylic acid,
  • Analgin,
  • Capsaicin.

Narcotic analgesics are often used:

  • Opioid tramadol,
  • Opioid codeine,
  • Oxycodo opioids,
  • Hydrocodo.

Narcotic analgesics are used strictly under the complete supervision of a physician, depending on the nature of the disease of rheumatoid arthritis, so that the patient does not become addicted during treatment. Non-narcotic drugs are used in a mild form of rheumatism as an analgesic and pain reliever.

Arthritis is an acute form of the inflammatory process in the joints, provoked by various types of pathogens. To cure the pathology and avoid complications, timely diagnosis and, corresponding to the form and stage of the disease, a course of treatment are necessary. In the case when a bacterial infection acts as a provocateur of inflammation, the therapeutic complex necessarily includes taking antibiotics for arthritis.

Read about treating knee arthritis at home. Check with your doctor before using the prescriptions in this article.

The feasibility of treatment with antibacterial drugs

Different types of pathology have different causes. Accordingly, antibacterial treatment should be used only when the cause of the pathology is pathogenic microflora:

  1. Septic (infectious) arthritis is inflammation caused by the entry of pathogenic microflora into the synovial membrane of the joint. The process can occur both due to direct infection through open trauma or surgical manipulations, and due to the presence of another focus of infectious inflammation in the body. The development of infectious arthritis is provoked by gram-positive and gram-negative strains: streptococci, staphylococci, mycoplasma, anaerobes, enterobacteria.
  2. The reactive form of arthritis manifests itself after the transferred intestinal and urogenital diseases, as well as infections of the respiratory system and nasopharynx. The main difference between reactive arthritis and infectious arthritis is in the complex infectious-immune nature of the disease. Pathogenic microorganisms are not directly introduced into the joint; instead, immune complexes are deposited on the synovial membrane, provoking an abnormal production of pro-inflammatory cytokines within the membrane, resulting in an inflammatory response of the joint tissues – infectious synovitis. Microorganisms that cause reactive inflammation: chlamydia, pneumococcus, mycoplasma, enterobacteria, Lyme borreliosis.

Antibiotic treatment is most appropriate for infectious and reactive arthritis, however, such a need may also arise for other types of joint pathology:

Therapy rarely requires treatment with antibacterial drugs. Such a need arises in the acute form of the disease or complications during relapses, due to the course of infectious diseases in the body.

If the immune system normally protects the body from viruses and bacteria, but in this pathology, it attacks healthy joint tissues, and immune complexes, settling through the bloodstream in the synovial membrane, provoke the proliferation of harmful cells and destroy healthy ones. With inflammation and infectious diseases, autoimmune pathology can provoke the introduction of pathogenic bacteria into the joint. Thus, against the background of rheumatoid pathology, signs of an infectious type of disease develop.

In the acute form of rheumatic disease, antibiotics are prescribed mainly for arthritis of the joints of the foot and knee to reduce severe pain and inflammation, in case of ineffectiveness of other anti-inflammatory drugs.

These types of diseases are not septic pathologies, therefore they are not treated with antimicrobial agents. An exception is possible in cases when, in parallel with the course of the disease, an infectious agent enters the joint. This can be due to injury, surgery, or a reaction to inflammation in other organs.

Signs of infection

Regardless of the type of joint inflammation, in the presence of an infectious pathogen, characteristic inflammatory symptoms are added to the usual manifestations of arthritis:

  1. Acute pain syndrome appears immediately after the inflammatory process. Since infectious arthritis has an asymmetrical way of affecting the joints, the pain syndrome is localized on a specific group of joints.
  2. In the area of ​​the inflamed joint, increasing swelling is observed.
  3. The skin turns red, when palpating, local hyperthermia of the joint is felt.
  4. The general condition worsens, the general body temperature rises, chills and fever, nausea and vomiting may be present.

Septic arthritis develops in a fairly short time after infection – from 2 days to a week. Signs of reactive pathology can appear within a month after the disease-provocateur. The symptoms are more progressive. And also a classic manifestation of reactive inflammation is Reiter’s syndrome, when, in addition to damage to the joints, the infection affects the eyes and genitourinary organs.

Treatment regimens

The main task in the treatment of rheumatoid arthritis is to suppress the abnormal activity of the immune system, normalize its work and eliminate the symptoms of inflammation.

To eliminate pain and swelling, non-steroidal anti-inflammatory drugs, ointments and gels based on them are used. The treatment regimen for autoimmune arthritis includes basic and biological immunosuppressants, as well as glucocorticoids – steroid hormones with an immunosuppressive effect.

Antibiotics for rheumatoid arthritis occur during acute exacerbations, when basic cytostatics and steroid drugs cannot cope with suppressing the inflammatory process.

In the case when the relapse of the disease is provoked by infectious diseases of the respiratory tract, ENT organs or urogenital inflammations, antibiotic treatment is carried out in parallel with immunosuppressive drugs.

Arthritis of the septic group requires the primary prescription of antibacterial drugs.

For gram-positive and gram-negative strains, antibiotics of a different spectrum of action may be needed. The course of antibiotic therapy is from 7 days to two weeks, the duration depends on the type of bacteria and the stage of inflammation.

Longer use of drugs is also not recommended, as it causes severe adverse reactions. The choice of medication also depends on which joints of the body are affected.

So, with a reactive form of arthritis, inflammation often affects the lower extremities, and antibiotics are aimed at treating urinary infections and the gastrointestinal tract.

Diagnosis and antibiotic therapy

The consultation and diagnosis of a rheumatologist or arthrologist will help determine the cause of joint inflammation and prescribe the correct course of treatment.

A visit to a specialist begins with taking an anamnesis. It will be necessary to remember how long ago unpleasant symptoms began to bother you and whether their appearance was preceded by an injury or any disease. To make a diagnosis, you need answers to some questions:

  1. Whether the pain syndrome bothers you. If so, how often and how strong is it?
  2. Are the joints swelling up?
  3. Is there hyperthermia of the skin in the area of ​​the inflamed joint?
  4. Has your general health worsened: high body temperature, chills, fever, rash?
  5. Is there a parallel malaise from the genitourinary organs, gastrointestinal tract or eyes?

Further, an examination of the affected joints and hardware diagnostics – X-ray, ultrasound, CT and MRI will follow.

Laboratory tests – general and biochemical blood tests, as well as sampling of synovial fluid for research and a culture tank – will help to accurately determine the type of infection.

Antibiotics for arthritis and arthrosis are prescribed according to the class of pathogenic microflora that aroused the inflammatory process. In addition to this factor, when prescribing antibacterial drugs, experts take into account some data:

  1. Analysis for individual sensitivity and allergic reactions to the drug.
  2. Patient age – children, adults and the elderly need different drug adjustments and dosages.
  3. The presence of chronic diseases.
  4. Pregnancy and breastfeeding.
  5. Combination with other drugs for arthritis.
  6. If more than one type of antibiotic is required, the degree of interaction and the possible increase in side effects are taken into account.

Most antibiotics have a faster anti-inflammatory effect when given by injection. However, some are better absorbed orally.

The doctor prescribes the intake and dosage of drugs. It is strictly forbidden to start taking antibiotics on your own or change their dosage without consulting your doctor.

Antibiotics of the penicillin group are used against infections of the respiratory tract and other strains of the gram-negative group. Most often, antibiotics of the penicillin group are prescribed for the treatment of rheumatoid arthritis, when the use of basic immunosuppressants does not bring relief:

  • Amoxicillin is a drug of the penicillin group with a wide spectrum of action on gram-positive and gram-negative types of microorganisms. It is used in the treatment of tonsillitis, pneumonia, otitis media, sinusitis, Lyme disease, meningitis, sepsis and infectious diseases of the gastrointestinal tract.
  • Ampicillin is a semi-synthetic broad-spectrum antibiotic used in the treatment of infections of the respiratory tract, gastrointestinal tract and genitourinary bacteria. In addition to gram-negative bacteria, it acts on a number of gram-positive microorganisms – Escherichia coli, Salmonella, Shigella, influenza sticks.
  • Carbenicillin – the drug is active in the fight against gram-negative bacteria Pseudomonas aeruginosa and some types of anaerobic strains. The substance is prescribed for the treatment of pneumonia, otitis media, purulent complications, sepsis, urinary infections, infectious inflammation of the skin, soft tissues and joints.

Penicillin antibiotics are not effective against staphylococcal strains. In addition, many patients have an increased sensitivity to penicillin, which excludes its use in the treatment of arthritis.

Third-generation cephalosporins are highly effective in treating a wide range of bacteria, but are less toxic. Therefore, in the treatment of arthritis, they are used more often than penicillin.

The drugs in this class include:

  • Ceftazidime;
  • Cefoperazone;
  • Cefazolin;
  • Cefotaxime;
  • Ceftriaxone.

All antibiotics have a similar spectrum of action and are most active in the fight against streptococci, gonococci, meningococci. Ineffective against – staphylococci, green streptococci and enterobacteria.

Cephalosporins and penicillins belong to the class of beta-lactams, therefore, cross-allergic reactions to both types of antibiotics are often noted.

Macrolides belong to the class of the least toxic antibiotics and are prescribed in cases of allergy to beta-lactams.
Natural Erythromycin and its semisynthetic derivatives – Roxithromycin and Clarithromycin, as well as azalide Azithromycin have an effective effect on gram-positive strains of staphylococci, streptococci, as well as meningococci, gonococci, chlamydia and mycoplasma.

Enterobacteriaceae, E. coli and Pseudomonas aeruginosa, Salmonella and Mycobacterium tuberculosis are resistant to antibiotics of this type.

A group of broad-spectrum antibiotics that, depending on dosage and concentration, are effective against most gram-positive and gram-negative bacterial strains. Tetracycline antibiotics are used for urogenital infections and arthritis of the knee and legs. Among the drugs of the tetracycline group are prescribed:

  • Tetracycline;
  • Metacyclin;
  • Doxycycline.

Antimicrobial drugs and a synthetic analogue of antibiotics. Highly effective in the treatment of intestinal bacteria and most gram-negative strains, as well as gram-positive pneumococci and staphylococci. And also fluoroquinolones are used in the fight against mycobacterium tuberculosis. In the treatment of infections that cause arthritis, second-generation drugs are used:

  • Ofloxacin;
  • Lemefloxacin;
  • Ciprofloxacin;
  • Pefloxacin.

If the previous groups of antibacterial agents cannot overcome the infectious agent of arthritis, experts resort to using Vancomycin. This antibiotic for bacterial arthritis and arthrosis of the joints has a wide range of effects on the largest number of pathogenic microorganisms. However, due to increased toxicity, it has a high probability of side effects.


Treatment with antibacterial drugs has a number of contraindications for use:

  1. Diseases of the gastrointestinal tract.
  2. Chronic kidney and liver diseases.
  3. Heart failure.
  4. Hypersensitivity and allergy to drug components.
  5. Pregnancy and breastfeeding.

If the above features are present, you must inform your doctor about them before starting antibiotic therapy.

Treatment with antibacterial drugs is effective in treating septic diseases of the joints, but is harmful to the beneficial bacteria in the body. Therefore, starting treatment with antibiotics, it is necessary to take care of the restoration of the body and the intake of probiotics.

When faced with a bacterial cause of joint disease, do not hesitate. Timely diagnosis and the correct course of antibiotic treatment will help to effectively fight harmful infections and restore health and functionality to your joints.

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