There are several basic ways to successfully treat gout. It is worth noting that primary gout arising from the hereditary predisposition of the individual is not treatable. Medication for gout
Secondary gout occurs mainly due to an unfavorable lifestyle (obesity, poor nutrition, etc.) and, in principle, also cannot be cured completely. However, treatment of gout with medications can relieve the patient of the symptomatic manifestations of the disease, slightly improve the general condition of the patient.
If a complete cure of the disease is not possible, you can still direct the treatment to get rid of the symptoms. Drug treatment is necessary to:
- Stop acute attacks.
- Reduce pain, inflammation.
- Prevent future attacks.
- Prevent the formation of tofus.
- Prevent the formation of kidney stones.
There are many drugs used to treat the disease. The most used drugs:
- NSAIDs (Ibuprofen, Diclofenac).
- Medications that lower uric acid levels (Probenecid, Benzobromaron, Allopurinol).
NSAIDs without cortisone to relieve inflammation and pain
Drugs in this group have anti-inflammatory, analgesic effects. Medication for NSAIDs should not last long. NSAIDs are taken in small doses so as not to damage the stomach, intestinal mucosa, and not cause ulcers and bleeding.
“Diclofenac” and “Ibuprofen” – drugs that suppress pain in the legs, significantly reducing inflammation in the joints. They are not suitable for causal therapy.
Among the side effects of the drugs are:
- gastrointestinal discomfort;
In most cases, the drugs are well tolerated. Ibuprofen should not be taken if there is serious kidney disease. The prolonged use of ibuprofen affects the cardiac system. Before using it, be sure to consult your doctor. It is also worth studying the instructions to ensure maximum safety for the body after taking it.
Diclofenac acts quickly enough for two hours. After taking the pill, the pain subsides, the effect lasts up to 6 hours.
Diclofenac Sodium is available over-the-counter. It is most suitable for the treatment of intense pain in the legs and joints since side effects do not bother. But the duration of action is much shorter.
“Colchicine”: properties, side effects
It is administered orally, in the form of tablets, or is used intravenously. There are tablets in two different doses: 0.5 and 0.6 milligrams per 1 tablet. It is better to use the drug orally since there is a risk of poisoning with the drug if injections are used.“Colchicine” is a drug used to treat an acute attack of gout. The medicine has a very important role in the treatment of gout, although there are many unresolved questions about the exact mode of action. The medical value of the substance is recognized in 1810.
“Colchicine” has anti-inflammatory properties, is not an analgesic (anesthetic), does not affect the excretion of uric acid from the body. It has a depressing effect, reduces the intensity of acute attacks of gout. It can be used as a preventative measure on a regular basis.
There are cases of overdose “Colchicine.” The following side effects may occur:
- hair loss;
“Colchicine” should not be taken by pregnant women and people who have an allergic reaction to the active substance of the drug.
Why are corticosteroids necessary?
Corticosteroids are used mainly by patients who do not tolerate either NSAIDs or Colchicine. Or, these drugs did not have the desired effect. These drugs include Prednisone and Cortisone.
Patients with acute episodes of the disease usually receive daily doses of Prednisolone in the range of 20-50 milligrams or similar, for three to four days. Then the dose is gradually reduced over one to two weeks.
Medications work, like representatives of non-steroidal anti-inflammatory drugs, with an acute attack of gout. They stop inflammation. Medications are taken orally in the form of tablets or injected directly into the joint to accelerate the action.
“Cortisone” is used to treat inflammatory diseases. It is taken only in severe cases and only for several days. Sometimes the doctor inserts it directly into the inflamed joint. The use of “Cortisone” for a long time is not recommended, since side effects may occur:
Uric acid-lowering drugs
Medicines used to treat the chronic course of the disease lead to rapid changes in uric acid levels. Attacks of the disease, pain in the legs, stop as soon as the drug begins to act and stabilizes the level of uric acid.
“Benzbromarone” and “Probenecid” contribute to the excretion of uric acid through the kidneys. But they can lead to the formation of kidney stones. Therefore, when using drugs, it is important to drink plenty of water.
The medicine is effective after some time, there may initially be a temporary worsening of symptoms. Since with their use, uric acid crystals dissolve and again enter the bloodstream. Only then excreted from the body.
Therefore, “Benzobromarone” and “Probenecid” are not suitable for the treatment of acute attacks of gout. But they quickly suppress pain in the legs and joints, relieve inflammation.
For the treatment of the chronic course of the disease, “Allopurinol” is prescribed. This drug works by blocking, reducing the production of uric acid. When using it, you need to drink about eight glasses of water per day. It is necessary to exclude alcoholic beverages, include foods containing vitamin C in the diet. Excess vitamin C causes kidney stones.
Medicine can cause various undesirable side reactions:
In rare cases, its use leads to itching, blood in the urine, eye irritation, swelling of the lips and oral cavity, loss of appetite, sudden weight loss.
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