Ankylosing spondylitis is a chronic disease of the joints when the spine is affected first, and then the sacroiliac joints. Pathology is inherited, manifests itself at the age of 20-30, and occurs mainly in men. Such ailment also negatively affects the work of the whole organism, affecting the heart, kidneys, lungs.
Forms and stages of development
|Visceral||Damage to internal organs: heart, kidneys, lungs|
|Central||Only affects the spine|
|Rhizomelic||Hip or shoulder joint suffers|
|Scandinavian||Lesion of small joints of the hand and foot|
|Peripheral||Destruction of distal joints: elbow, knee|
As a result of the disease, fusion (ankylosis) of the joints occurs. Inflammation provokes the production of synovial fluid, fibrin protein is deposited. The cartilage is gradually destroyed. Further, membranes are formed between the vertebrae, because the disease affects the intervertebral discs and ligaments. As a result, the structures are completely fettered and the spine becomes completely immobile. Therefore, it is very important to recognize ankylosing spondyloarthritis in the early stages, before irreparable bone changes have occurred.Is exercise useful in the treatment of ankylosing spondylitis?
Causes and pathogens
The likelihood of ankylosing spondylitisis 20% higher with a family history of pathology.
Medicine has not yet established the exact etiology of the disease. Although it is known that these include:
- infectious lesions;
- joint or bone injuries;
- hormonal disruptions;
- stressful situations.
Is ankylosing spondylitis inherited?
The risk of developing pathology increases 3 times if relatives are carriers of ankylosing spondylitis. The true sources of the disease have not been established, but scientists have proven that one of the reasons is the presence of the HLA-B27 gene. It was found that in 9 out of 10 patients, the antigen is present in the DNA. But it is important to understand that not all people with it suffer from this disease. The possibility of developing ankylosing spondyloarthritis under the influence of the environment is not excluded.
The presence of the HLA-B27 antigen leads to weakness and the joints become susceptible to infection. The immune system mistakes its own tissues for viruses and fights them by producing antibodies. The body compensates for the destruction of organs and, as a result, the formation of excess bone tissue occurs, which leads to the stubbornness of the spine and numbness of the nerves.
Doctors and scientists are still unable to cure ankylosing spondylitis. You can only alleviate the symptoms and partially restore the work of the spine. Research is underway on the possibility of surgery and its effectiveness. There is a version that the recognition of defective tissues will prevent the transmission of disease propensity and prevent the appearance of aggressive cells. A treatment method is also being considered, which involves the introduction of stem cells into damaged tissues. But such a procedure is expensive and is carried out only in some foreign clinics.
|Group of drugs||Representatives|
The systematic use of non-steroidal anti-inflammatory drugs leads to adaptation of the body and a decrease in the effectiveness of drugs. It is recommended to change the drug every 2-3 months.
Severe stages of the disease involve the use of glucocorticosteroid hormones, immunosuppressive drugs and antidepressants. Regular examinations and consultations of a doctor are recommended, who will adjust the therapy regimen, taking into account the need for such factors: physiotherapy complexes, health resort treatment, correction of the dosage of medicines and lifestyle.COMPLICATIONS OF ANKYLOSING SPONDYLITIS